From spacing to seeds per acre
An acre is 43,560 square feet, or 6,272,640 square inches. Each seed occupies a rectangle of row width times in-row spacing, so seeds per acre = 6,272,640 / (row width in inches x seed spacing in inches).
Growers usually work backward: pick a target population, then set the meter for the spacing that delivers it. Final plant stand is lower than seeds dropped because not every seed emerges.
Why speed is tricky
At 5 mph with 6.3 inch spacing each row drops about 14 seeds every second. Faster planting means the meter must singulate seeds more quickly and the row unit must stay steady on rough ground, or spacing and depth suffer.